My research interests are in Computational Biology, and more specifically in developing quantitative models for all levels of gene regulation, including transcription, chromatin, and translation. Selected publications:
 |
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.
Nature Biotechnology, 2012.
|
 |
Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast.
Nature Genetics, 2012.
|
 |
Genome-wide measurement of RNA secondary structure in yeast.
Nature, 2010.
|
 |
From DNA sequence to transcriptional behaviour: a quantitative approach
Nature Reviews Genetics, 2009.
|
 |
The DNA-Encoded Nucleosome Organization of a Eukaryotic Genome.
Nature, 2009.
|
 |
Predicting expression patterns from regulatory sequence in Drosophila segmentation.
Nature, 2008.
|
 |
The role of site accessibility in microRNA target recognition.
Nature Genetics, 2007.
|
 |
A Genomic Code for Nucleosome Positioning.
Nature, 2006. The New York Times, 2006.
|
|