Prof. Eran Segal

Department of Computer Science And Applied Math
CS & Math Building 2, Room 111
Weizmann Institute of Science

Tel: +972-8-934-4282

My research in Computational and Systems Biology focuses on Nutrition, Genetics, Microbiome, and Gene Regulation and their effect on health and disease. We aim to develop personalized nutrition and personalized medicine. Selected publications:

Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.
Science, 2015.

Artificial sweeteners induce glucose intolerance by altering the gut microbiota.
Nature, 2014. The New York Times.

Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis.
Cell, 2014.

In pursuit of design principles of regulatory sequences.
Nature Reviews Genetics, 2014.

Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.
Nature Biotechnology, 2012.

Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast.
Nature Genetics, 2012.

Genome-wide measurement of RNA secondary structure in yeast.
Nature, 2010.

From DNA sequence to transcriptional behaviour: a quantitative approach
Nature Reviews Genetics, 2009.

The DNA-Encoded Nucleosome Organization of a Eukaryotic Genome.
Nature, 2009.

Predicting expression patterns from regulatory sequence in Drosophila segmentation.
Nature, 2008.

The role of site accessibility in microRNA target recognition.
Nature Genetics, 2007.

A Genomic Code for Nucleosome Positioning.
Nature, 2006. The New York Times.