Prof. Eran Segal

Incumbent of the Soretta and Henry Shapiro
Career Development Chair

Department of Computer Science And Applied Mathematics
Ziskind Building, Room 149

Tel: +972-8-934-4282
eran.segal@weizmann.ac.il


My research is in Computational and Systems Biology and focuses on two major directions: Developing quantitative models for all levels of gene regulation, including transcription, chromatin, and translation; and Studying the relationship between nutrition, health, and gut microbes in human individuals (check out our Personal Nutrition Project). Selected publications:

Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.
Nature Biotechnology, 2012.

Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast.
Nature Genetics, 2012.

Genome-wide measurement of RNA secondary structure in yeast.
Nature, 2010.

From DNA sequence to transcriptional behaviour: a quantitative approach
Nature Reviews Genetics, 2009.

The DNA-Encoded Nucleosome Organization of a Eukaryotic Genome.
Nature, 2009.

Predicting expression patterns from regulatory sequence in Drosophila segmentation.
Nature, 2008.

The role of site accessibility in microRNA target recognition.
Nature Genetics, 2007.

A Genomic Code for Nucleosome Positioning.
Nature, 2006. The New York Times, 2006.