Dr. Eran Segal

Incumbent of the Soretta and Henry Shapiro
Career Development Chair

Department of Computer Science And Applied Mathematics
Ziskind Building, Room 149

Tel: +972-8-934-4282
eran.segal@weizmann.ac.il


My research interests are in Computational Biology, and more specifically in developing quantitative models for all levels of gene regulation, including transcription, chromatin, and translation. Selected publications:

From DNA sequence to transcriptional behaviour: a quantitative approach
E. Segal and J. Widom.
Nature Reviews Genetics, 2009.

The DNA-Encoded Nucleosome Organization of a Eukaryotic Genome.
N. Kaplan, I.K. Moore, Y. Fondufe-Mittendorf, A.J. Gossett, D. Tillo, Y. Field, E.M. LeProust, T.R. Hughes, J.D. Lieb, J. Widom, E. Segal.
Nature, 2009.

Predicting expression patterns from regulatory sequence in Drosophila segmentation.
E. Segal, T. Sadka, M. Schroeder, U. Unnerstall, U. Gaul.
Nature, 2008.

The role of site accessibility in microRNA target recognition.
M. Kertesz, N. Iovino, U. Unnerstall, U. Gaul, E. Segal.
Nature Genetics, 2007.

A Genomic Code for Nucleosome Positioning.
E. Segal, Y. Fondufe-Mittendorf, L. Chen, A. Thastrom, Y. Field, I.K. Moore, J.Z. Wang, J. Widom.
Nature, 2006. The New York Times, 2006.

Module Networks: Identifying Regulatory Modules and their Condition Specific Regulators from Gene Expression Data.
E. Segal, M. Shapira, A. Regev, D. Pe'er, D. Botstein, D. Koller, N. Friedman.
Nature Genetics, 2003.