The Weizmann Institute of Science Faculty of Mathematics and Computer Science Computer Science Seminar Lila Kari Department of Computer Science University of Western Ontario London, Ontario, Canada will speak on HOW TO COMPUTE WITH DNA Abstract: Biomolecular computing is a new computational paradigm that employs (bio)molecule manipulation to solve computational problems, while at the same time exploring natural processes as computational models. The excitement generated by the first successful experiment (Adleman, 1994) was due to the fact that computing with biomolecules (mainly DNA) offered an entirely new way of performing and looking at computations. The main idea was that data could be encoded in DNA strands, and molecular biology techniques could be used to execute computational operations. This talk addresses the issues of the computational power of DNA computing in vitro (in the molecular biology laboratory) and in vivo (as performed by unicellular organisms). Besides the novelty of the approach, biomolecular computing has the potential to outperform electronic computers. For example, DNA computations may use a billion times less energy than an electronic computer, while storing data in a trillion times less space. Moreover, computing with DNA is highly parallel: in principle there could be billions or trillions of DNA molecules undergoing chemical reactions, that is, performing computations, simultaneously. The lecture will take place in the Lecture Hall, Room 1, Ziskind Building on Monday, December 20, 1999 at 14:30